C
URVA
DE
CRESCIMENTO
DAS
EMISSÕES
OTOACÚSTICAS
PRODUTO
DE
DISTORÇÃO
EM
NEONATOS
R
EV
A
SSOC
M
ED
B
RAS
2014; 60(6):591-598
597
parado com os outros paradigmas (P1 e P2), e os valores
do
slope
do P geral forammaiores do que os obtidos nos P1
e P2. A média dos valores do
slope
no P geral foi de 10,05
na orelha direita e 8,85 na orelha esquerda.
C
ONCLUSÃO
Os limiares de surgimento foram em média 30 dB NPS
em 2.000 Hz e 35 dB NPS em 4.000 Hz, sendo, portanto,
os limiares de surgimento melhores na frequência de
2.000 Hz comparada a 4.000 Hz.
Não foi observada diferença nos valores de
slope
ob-
tidos nas curvas de crescimento das EOAPD; porém, as
curvas tinham inclinação mais íngreme nas intensidades
mais fracas (P1) e mais linear nas intensidades modera-
das (P2), sugerindo que a análise visual do gráico relete
a compressão coclear.
A
GRADECIMENTOS
A Peter Bray e Lee VanMiddlesworth, da Otodynamic, que
colaboraram com conhecimento técnico todas as vezes que
foram consultados. À Prof. Erika Fukunaga, pela análise
estatística. AMirtes, Sonia e Daniel, secretários da pós-gra-
duação, pela ajuda constante e imprescindível. À bibliote-
cária Sadia Hussein Mustafá, pelos artigos conseguidos e
icha catolográica. À Faculdade de Ciências Médicas da
Santa Casa de São Paulo e à Irmandade da Santa Casa de
Misericórdia de São Paulo. À Capes, pela bolsa de estudos
concedida. Aos responsáveis pelos neonatos, que aceita-
ram o convite para participar deste estudo.
S
UMMARY
Growth curve otoacoustic emissions distortion product
in neonates
Background:
The recording of otoacoustic emissions
(OAE) enabled us to prove that the cochlea is able not
only to receive sounds but also to produce acoustic energy.
Through the use of distortion-product otoacoustic emis-
sion measurements, the growth of the response was seen
according to the intensity of the sound stimulus presen-
ted (growth curve).
Objective:
to determine the thresholds for the emergen-
ce of distortion-product otoacoustic emissions (DPOAE)
on frequencies of 2000 and 4000 Hz with a stimulus
varying from 20 to 65dB SPL, and to establish the slope
values obtained in the growth curves.
Methods
: 39 neonates aged 5 to 28 days without risk in-
dicators of hearing loss were studied. The DPOAE growth
curves were obtained on the frequencies from 2000 Hz
and 4000 Hz with a level of intensity ranging from 20 to
65dB SPL divided into two paradigms (20 to 40dB SPL
and 40-65dB SPL).
Results
: there was a statistically signiicant difference in
the thresholds for the emergence of DPOAE depending
on the criteria used. The thresholds were on average higher
at 4000 Hz than 2000 Hz and the slope was higher on
average at 2000 Hz than 4000 Hz, although not statisti-
cally signiicant in either case.
Conclusion
: the thresholds were on average 30dB SPL at
2000Hz and 35dB SPL at 4000Hz. The slope values varied
between 3 and 4 on average, reaching 15 in some cases.
Keywords
: spontaneous otoacoustic emissions, hearing
tests, hearing, newborn.
R
EFERÊNCIAS
1. Kemp, D.T. Stimulated acoustic emissions from within the human auditory
system. J Acoust Soc Am 1978; 64(5):1386-91.
2. RuggeroM, RichN, Naryan SS, Robles L. Basilar-membrane responses to tones
at the base of the chinchilla cochlea. J Acoust Soc Am 1997; 101(4):2151-63.
3. Gorga MP, Neely ST, Dierking DM, Kopun J, Jolkowski K, Groenenboom
K et al. Low-frequency and high-frequency cochlear nonlinearity in humans.
J Acoust Soc Am 2007; 122(3):1671-80.
4. Abdala C. Distortion product otoacoustic emission (2i-f2) amplitude growth
in human adults and neonates. House Ear Institute. J Acoust Soc Am 2000;
107(1):446-56.
5. Kemp DT. Otoacoustic emissions, their origin in cochlear function, and
use. Br Med Bull 2002; 63:223-41.
6. Dubno JR, Horwitz AR, Ahlstrom JB. Estimates of basilar-membrane
nonlinearity effects on masking of tones and speech. Ear Hear 2007; 28(1):2-
17.
7. Almeida PP. Crescimento das emissões otoacústicas evocadas-produto de
distorção: estudo em neonatos. [Dissertação]. São Paulo: Faculdade de
Medicina, Universidade de São Paulo, 2010.
8. Gorga MP, Neely ST, Dorn PA, Konrad-Martin D. The use of distortion
product otoacoustic emission suppression as an estimate of response growth.
J Acoust Soc Am 2002; 111(1):271-84.
9. Gehr DD, Janssen T, Michaelis CE, Deingruber K, Lamm K. Middle ear and
cochlear disorders result in different DPOAE growth behavior: implications
for the differentiation of sound conductive and cochlear hearing loss. Hear
Res 2004; 193(1-2):9-19.
10. Janssen T, Niedermeyer HP, Arnold W. Diagnostics of the cochlear ampliier
by means of distortion product otoacoustic emissions. ORL J
Otorhinolaryngol Relat Spec 2006; 68(6):334-9.
11. Ballard JL, Khoury JC, Wedig K, Wang L, Eilers-Walsman BL, Lipp R. New
Ballard Score, expanded to include extremely premature infants.
12. Joint Committee on Infant Hearing 2007 Position Statement. ASHA 1994;
36:38-41.
13. Almeida PP, Sanches SGG, Carvallo RMM. Limiar da função de crescimento
das emissões otoacústicas por produto de distorção em neonatos Pró-Fono
2010; 22(4):409-14.
14. Kummer P, Janssen T, Wolfgang A. The level and growth behavior of 2f1-f2
distortion product otoacoustic emission and its relationship to auditory
sensitivity in normal hearing and cochlear hearing loss. J Acoust Soc Am
1998; 103(6):3431-44 .