Set - Out - English

artits

404

ssoc

ras

2014; 60(5):404-414

guidelines in focus

Late-onset hypogonadism or ADAM: treatment

ipogonadismo masculino

tardio

aem

tratamento

Authorship:

Brazilian Society of Endocrinology; Brazilian Society of Urology

Participants:

Martits AM, Costa EMF, Nardi AC, Nardozza Jr. A, Facio Jr. FN, Faria G, Bernardo WM

Conflict of interest:

no conflict of interest informed.

Final draft:

March 21

, 2014

http://dx.doi.org/10.1590/1806-9282.60.05.005

The Guidelines Project, an initiative of the Brazilian Medical Association, aims to combine information from the medical field in order to standar-

dize procedures to assist the reasoning and decision-making of doctors.

The information provided through this project must be assessed and criticized by the physician responsible for the conduct that will be adopted, de-

pending on the conditions and the clinical status of each patient.

escription

the

evidence

collection

method

The recommendations were supported by the evidence ob-

tained in the Medline, Embase, Lilacs and Cochrane data-

bases, using the following strategies: ((((((aged OR aging)

AND (androgens/deficiency OR hypogonadismOR testos-

terone/deficiency)) AND (hormone replacement therapy)

AND (aging/blood OR androgens/blood* OR androgens

OR androstenedione/blood OR body mass index OR body

Weight OR dehydroepiandrosterone/blood* OR dehydroe-

piandrosterone sulfate/blood* OR dihydrotestosterone/

blood OR gonadal steroid hormones/blood* OR gonado-

tropins/blood OR gonadotropins OR pituitary hormones

OR hormones/blood* OR hormones/physiology OR hypo-

gonadism/blood OR hypotalamo-hypophyseal systemOR

immunoassay OR luteinizing hormone OR luteinizing

hormone/blood OR radioimmunoassay OR radioimmu-

noassay/methods OR radioimmunoassay/standards* OR

reagent kits, diagnostic/standards OR sex hormone-bin-

ding globulin/analysis OR testosterone OR testosterone/

blood* OR testosterone/metabolism OR hematocrit OR

liver function tests OR prostatic neoplasms OR continuity

of patient care OR consultation OR monitoring))) AND

(diagnosis/broad[filter]) AND (“last 5 years”[PDat]))) OR

(((((aged OR aging) AND (androgens/deficiency OR hypo-

gonadism OR testosterone/deficiency)) AND (hormone

replacement therapy) AND (aging/blood OR androgens/

blood* OR androgens OR androstenedione/blood OR

body mass indexOR body weight OR dehydroepiandros-

terone/blood* OR dehydroepiandrosterone sulfate/blood*

OR dihydrotestosterone/blood OR gonadal steroid hor-

mones/blood* OR gonadotropins/blood OR gonadotro-

pins OR pituitary hormones OR hormones/blood* OR

hormones/physiology OR hypogonadism/blood OR hypo-

talamo-hypophyseal system OR immunoassay OR lutei-

nizing hormone OR luteinizing hormone/blood OR ra-

dioimmunoassay OR radioimmunoassay/methods OR

radioimmunoassay/standards* OR reagent kits, diagnos-

tic/standards OR sex hormone-binding globulin/analysis

OR testosterone OR testosterone/blood* OR testostero-

ne/metabolismOR hematocrit OR liver function tests OR

prostatic neoplasms OR continuity of patient care OR con-

sultation OR monitoring))) AND (etiology/broad[filter])

(age OR aged OR aging) AND (andropause OR gonadal

OR deficiency OR hypogonadismOR hypogonadal) AND

(testosterone OR androsterone OR DHEA OR dehydroe-

piandrosterone OR androgen OR androgenic OR nandro-

lone OR replacement OR steroids OR anabolic OR sex OR

hormone) AND (muscles OR strength OR cognitive OR

function OR cognition OR mental OR performance OR

diabetic OR diabetes OR obesity OR body OR fat OR obe-

se OR mass OR hyperinsulinaemia OR adiposity OR libi-

do OR sexual OR behavior OR quality of life OR life style

OR lipids OR carbohydrates OR metabolism) (((age OR

aged OR aging) AND (andropause OR gonadal OR defi-

ciency OR hypogonadismOR hypogonadal) AND (testos-

terone OR androsterone OR DHEA OR dehydroepiandros-

terone OR androgen OR androgenic OR nandrolone OR

replacement OR steroids OR anabolic OR sex OR hormo-

ne))) AND (polycythemia OR prostatic neoplasms OR car-

diovascular diseases OR liver diseases OR sleep apnea syn-

dromes OR metabolic syndrome).