RAMB - Novembro 2017

unes

RLV

932

ssoc

ras

2017; 63(11):929-940

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nnex

Clinical question

What is the effectiveness of laser prostatectomy (PVP) in

patients with benign prostatic hyperplasia?

Structured question

•

P: Prostatic hyperplasia

•

I: Laser prostatectomy (photoselective vaporization of

the prostate [PVP])

•

C: Transurethral resection of the prostate

•

O: Effectiveness and harm

Search strategy

•

#1 – (Prostatic Hyperplasia OR Prostatic Hypertrophy

OR Prostatic Adenoma)

•

#2 – (Laser Therapy OR Laser OR Lasers OR Greenlight)

•

#3 – Random*

•

#4 – Systematic[sb]

RETRIEVAL = (#1 AND #2 AND #3) OR (#1 AND

#2 AND #4) = 367

((Prostatic Hyperplasia OR Prostatic Hypertrophy

OR Prostatic Adenoma) AND (Laser Therapy OR Laser

OR Lasers OR Greenlight) AND Random*)) OR ((Pros-

tatic Hyperplasia OR Prostatic Hypertrophy OR Pros-

tatic Adenoma) AND (Laser Therapy OR Laser OR Lasers

OR Greenlight) AND Systematic[sb]))

Articles retrieved

The obtaining of evidence to be used to analyze the clin-

ical question followed the steps of: elaboration of the clin-

ical question, structuring of the question, search for evi-

dence, critical evaluation and selection of evidence,

presentation of results and recommendations.

The bases of scientific information consulted were:

Medline via Pubmed, Embase, Central Cochrane and

Cochrane Library.

A total of 367 articles were retrieved, of which 22 were

selected after reading the title and abstract; of these 11

had the full text accessed to answer the proposed clinical

question (Table 1).

3-13

Inclusion and exclusion criteria

Phase III randomized controlled clinical trials, systemat-

ic reviews (with or without meta-analyzes), comparative

(or non-comparative) studies were included, and, in their

absence, the best evidence available to answer the clini-

cal question within the limits of PICO.

According to study design

Narrative reviews, case reports, case series, studies present-

ing preliminary results only were, in principle, excluded

from the selection. Systematic reviews and meta-analyzes

were used with the principle of retrieving references that

may have been lost since the initial search strategy. Con-

trolled clinical trials were assessed based on the Jadad

and GRADE

scores.

Language

We included studies available in Portuguese, English

or Spanish.

According to type of publication

Only full-text studies were considered for critical assessment.