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AMB G

uidelines

P

rogram

R

ev

A

ssoc

M

ed

B

ras

2017; 63(5):387

387

EDITORIAL

AMB Guidelines Program

P

rograma

D

iretrizes

da

AMB

W

anderley

M

arques

B

ernardo

1

*, F

lorentino

C

ardoso

1

1

Associação Médica Brasileira (AMB)

*Correspondence:

wmbernardo@usp.br http://dx.doi.org/10.1590/1806-9282.63.05.387

It has been 17 years of struggle, during which many have

participated. Naming these individuals is not necessary,

for they all continue to fight for the rights of patients,

and their names are not hidden, they are public who take

responsibility for what they think and write.

The struggle has been to keep the program running

funded with AMB’s own resources, without the support

of those who, exercising an eminently political function,

insist that there is a conflict of interest in the AMB guide-

lines. They are understandably unable to admit their own

economic and political conflicts, and to critically appraise

the fundamental elements of evidence-based guidelines.

The Guidelines Program is the space we have used to

convey recommendations whose sole purpose is to increase

benefits and reduce harm to patients. These recommen-

dations express the thoughts of experts and are written

primarily based on the best available evidence. Speaking

on the basis of the best available evidence implies know-

ing how to obtain it, criticize it, synthesize it and translate

it, considering the experience and expectations of both

doctors and patients.

Many specialists are involved in the development of

thousands of recommendations, distributed in more than

700 guidelines, which receive methodological guidance

from a technical team of the AMB itself, with experience

in systematic review and the language of guidelines.

The whole process begins with the elaboration of rel-

evant clinical doubts by specialists (in Brazil, our program

was the first to develop guidelines based on questions).

These doubts are structured in a PICO (Patient, Interven-

tion or Indicator, Comparison and Outcome) format,

seeking to facilitate the organization of questions and the

construction of search strategies. Searches are performed

minimally on Medline, and usually on more bases. The

selection of references is based on previously established

eligibility criteria (the main ones being PICO and design),

and this entire process is clearly displayed in the guideline’s

methodology section. After selection of evidence, data

regarding the characteristics of the studies, their biases

and outcomes of clinical interest are extracted. The

strength of evidence is estimated using grading systems

such as Oxford and GRADE. With such information in

hand, the authors are able to develop the recommendations

by estimating their level of uncertainty, and the magnitude

and precision of benefit and/or damage effects.

The specialists frommedical specialty societies that are

part of AMB are not mere validators of a previously prepared

text, but authors who, together with AMB’s technical team,

develop all stages of elaboration. After the guidelines are

finalized, all AMB specialty societies that did not participate

in the elaboration of that particular document are consult-

ed so that they have the opportunity to contribute.

In Brazil, unfortunately, apart from the AMB Guide-

lines Program, “they” are always producing “booklets” with

methodology for developing guidelines (true Portuguese

versions of international manuals). Despite all the resourc-

es they have, very little has been done. Moreover, what has

been done lacks a level of attention to evidence, medical

experience and, worse, attention to the patient’s needs,

operating through two health systems (private or govern-

ment-funded) divided into two guidelines that are NOT

based in evidence: 1. Guidelines without limits, in which

everything is accepted, and 2. Guidelines with strict limits,

according to which almost nothing can be accomplished.

The AMB Guidelines Program, regardless of what

“they” say, is reputable, very reputable, transparent, very

transparent, exempt, has method, and contradicts many

interests, including “theirs”. But it never contradicts the

interests of patients and, with all of its limitations result-

ing from these individuals’ constant boycott and omission,

it endures thanks to the willingness, dedication and self-

lessness of thousands of medical specialists. We are always

open to all criticism and suggestions from those who have

the interest and/or ability to do so.

R

eferences

1.

Bernardo WM. Cheers!!! Rev Assoc Med Bras (1992). 2016;62(9):809-810.

2.

Bernardo WM, Carneiro AV, Baracat EC. [Guidelines: unity and balance].

Rev Assoc Med Bras (1992). 2009;55(5):498-9.

3.

Bernardo WM. [Clinical guidelines in Brazilian health system]. Rev Assoc

Med Bras (1992). 2008;54:377.