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possible side effects and contraindications, so that the
procedure could be safely performed.
In all modalities of UVB phototherapy or PUVA, com-
plementary therapies such as topical vitamin D analogues,
corticosteroids and topical or oral retinoids may be associ-
ated for better control of psoriasis and other dermatoses.
1,7,8
One of the main indications of phototherapy is the
control of psoriasis. According to the Brazilian Consensus
of Psoriasis 2012, any form of phototherapy can be used
in this dermatosis. UVB is the first line for psoriasis, as it
is safer and more effective. It can be used in pregnant
women and children, and poses less risk of photoaging
and ophthalmological involvement, since it does not
require psoralens as adjuvants.
7
On the other hand, PUVA
is indicated as the best therapeutic option for extensive
areas of involvement, thick psoriatic patches and patients
with phototype III or greater.
1,5,9,10
In case 2, we chose
PUVA because the patient had extensive psoriasis and
thick plaques.
In vitiligo, repigmentation after treatment occurs due
to migration of melanocytes from the hair follicles to the
basal layer of the skin.
11
Phototherapy stimulates mela-
nogenesis and interferes with the inflammatory process
of the dermatosis.
1
In extensive vitiligo (as in the case
presented) PUVA with oral psoralen is the best therapeu-
tic option. Although many authors advocate UVB radia-
tion as the safest method, others indicate it only when
PUVA is contraindicated.
1,2
We opted for PUVA with oral
psoralen because of its effectiveness in extensive vitiligo.
The etiology of pityriasis alba is unknown but appears
to be related to xerosis and atopic eczema.
11
It mainly
affects the face, back and outer side of the arms, sometimes
posing a differential diagnosis with pityriasis versicolor.
11,12
The treatment of choice are emollients, sun protection
and the use of topical corticosteroids. Refractory cases
can be treated with PUVA.
13
The results of the sessions
exceeded expectations with the disappearance of most of
the lesions.
All three cases yielded excellent therapeutic results.
Good tolerance to phototherapy should be emphasized
without triggering relevant side effects. Thus, great psy-
chosocial impact and self-esteem was obtained, with im-
provement in patients’ quality of life.
R
eferences
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