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S

omatic

mutations

in

breast

and

serous

ovarian

cancer

young

patients

:

a

systematic

review

and

meta

-

analysis

R

ev

A

ssoc

M

ed

B

ras

2015; 61(5):474-483

483

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frequency of G/C transversion on

P53

gene alterations in breast cancers

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70. Van Emburgh BO, Hu JJ, Levine EA, Mosley LJ, Case LD, Lin HY, et al.

Polymorphisms in drug metabolism genes, smoking, and

P53

mutations

in breast cancer. Mol Carcinog. 2008; 47(2):88-99.

71.

Bozhanov SS, Angelova SG,

KRAS

teva ME, Markov TL, Christova SL, Gavrilov

IG, et al. Alterations in

P53

,

BRCA1

, ATM,

PIK3CA

, and HER2 genes and

their effect in modifying clinicopathological characteristics and overall

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72.

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GATA3

mutations define a

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73.

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TP53

and PI3K

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Breast Cancer Res Treat. 2012; 132(1):29-39.

74. FujitaM, Enomoto T, InoueM, Tanizawa O, Ozaki M, Rice JM, et al. Alteration

of the

P53

tumor suppressor gene occurs independently of K-ras activation and

more frequently in serous adenocarcinomas than in other common epithelial

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75.

Manderson EN, Presneau N, Provencher D, Mes-Masson AM, Tonin PN.

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TP53

mutations in human epithelial ovarian cancer.

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76.

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P53

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77.

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